Missoni Amos, now 35, left after high school, first for Milan, then on to Barcelona, New York, Paris, and Rome before circling back to Milan. After she and Amos married, she craved a home where they could put down roots back in the place they grew up. So the next year, after finding the ideal site, the couple enlisted Milan-based architect Aldo Cibic to build a four-bedroom house there. Missoni Amos insisted on handling the interiors herself. 

A custom rug by Missoni Home covers the living rooms floor. At far left vintage chairs wear a Pierre Frey fabric.Above custom acrylic shelving by Andrea Branzi divides the living room. A Paul Evans table sits atop a zebra rug in the living room. The dining room walls and ceiling flourish with a handpainted muraland matching curtainsby Pictalab. 

The Missoni brand is known for its embrace of bold colors and contrasting prints, and this same ethos informs the look of the house.A garden mural painted by Pictalab, an artist collective based in Milan, covers the dining room’s walls—and ceiling. Flamboyant marbles, including one nicknamed Missoni by the company that supplied it, and bold Josef Frank wallpapers for Svenskt Tenn define the bathrooms.The kitchen floor and walls are clad in a punchy artisanal tile.